Posts tagged with "Avocados"

Avocado discovery may lead to new leukemia treatment

May 3, 2021

With a host of nutritional benefits and a taste that satisfyingly tops off everything from salads to toast, avocados have become a dietary staple of millions—but recent research results point to some extra medicinal benefits offered by the popular fruit , as well, Study Finds reports.

Researchers from the University of Guelph in Ontario, Canada, have discovered a new avocado compound they say may open the door for better leukemia treatments.

More specifically, this compound appears to target and attack an enzyme that can be critical to cancer cell growth.

Researchers focused their attention on acute myeloid leukemia (AML), which doctors call the most dangerous variety of blood cancer. Most people diagnosed with AML are over 65 years old—and only about 10% survive for five years post-diagnosis.

Importantly, leukemia cells house large amounts of an enzyme called VLCAD, which is involved in their metabolism. “The cell relies on that pathway to survive,” says Dr. Paul Spagnuolo, Department of Food Science, in a university release. “This is the first time VLCAD has been identified as a target in any cancer.”

Spagnuolo and his team tested various nutraceutical compounds in an attempt to find any substance capable of fighting VLCAD.

“Lo and behold, the best one was derived from avocado,” Spagnuolo notes.

“VLCAD can be a good marker to identify patients suitable for this type of therapy. It can also be a marker to measure the activity of the drug,” he continues. “That sets the stage for eventual use of this molecule in human clinical trials. There’s been a drive to find less toxic drugs that can be used.”

According to Study finds, right now, about half of all older AML patients enter palliative care. Others opt for chemotherapy, but that often does more harm than good.

“We completed a human study with this as an oral supplement and have been able to show that appreciable amounts are fairly well tolerated,” Spagnuolo concludes.

The study appears in the journal Blood.

Research contact: @StudyFinds

America will run out of avocados in three weeks if Trump shuts southern border

April 3, 2019

President Donald Trump’s has threatened again this week to close the U.S.-Mexico border, continuing his all-out effort to coerce the political leaders of both nations to block South American immigrants from coming across.

However, even a brief shutdown at America’s southern border would strain the economies of both nations by disrupting billions of dollars in trade, about $137 billion of which is in food imports.

Nearly 50% of all imported U.S. vegetables and 40% of imported fruit are grown in Mexico, according to the latest data from the United States Department of Agriculture.

From avocado toast to margaritas, American shoppers—who are heavily reliant on Mexican imports of fruit, vegetables, and alcohol—quickly would become bereft.

Indeed, the stoppage quickly would become “hard to swallow” for U.S. residents—especially those who love avocados, according to a report by Reuters. Those of us north of the border would run out of avocados in three weeks, if imports from Mexico were cut off, according to  Steve Barnard, CEO of Mission Produce, the largest distributor and grower of avocados in the world.

“You couldn’t pick a worse time of year because Mexico supplies virtually 100% of the avocados in the United Stated right now. California is just starting and they have a very small crop, but they’re not relevant right now and won’t be for another month or so,” Barnard said in an interview with Reuters.

In addition to avocados, the majority of imported tomatoes, cucumbers, blackberries, and raspberries come from Mexico. While there are other sources of produce globally, opening those trade channels would take time.

And shortages of fruit and vegetables will rack up the already-soaring prices at the cash register.

On the other side of the border, Mexico is the largest importer of U.S. exports of refined fuels like diesel and gasoline, some of which moves by rail. It is unclear if rail terminals would be affected by closures.

Research contact: @Reuters